Bliss© was first developed and tested for hematology and oncology applications, to improve care by alleviating patient distress during invasive and painful procedures. In particular, the first clinical study dedicated to Bliss© evaluated its efficacy during osteo-medullary biopsies in haematology. Bliss© Digital Therapeutics uses a VR headset and an audio headset specifically optimized to provide relief to patients by reducing pain and anxiety during medical procedures.