EvidenceMD is an AI-powered clinical decision support platform designed for physicians, clinicians, and biomedical researchers. It provides transparent, step-by-step clinical reasoning grounded in peer-reviewed evidence from leading medical journals such as NEJM, JAMA, The Lancet, and Nature Medicine. The platform integrates four core functionalities: evidence-based clinical reasoning, an AI medical scribe for real-time documentation, citation-backed literature search, and a developer-friendly medical AI API. It enables healthcare professionals to make informed, research-backed decisions quickly and with confidence, supporting complex patient management, hypothesis validation, and academic publishing.