We are developing innovative solutions that lead to better health and a learning healthcare system by empowering people with their digital health data. Hugo is an easy-to-use, cloud-based solution that enables the secure acquisition, harmonization, and utilization of health-related data from electronic health record and billing systems, surveys, wearables, sensors and medical devices. By automating a process that easily and securely enables people to collect and share their health information — Hugo solves the problem of interoperability. Furthermore, by matching people and their information in data partnerships with research opportunities and clinical care the potential exists to unleash a personal digital health data revolution that will transform health care and provide a solution that leads to better knowledge generation in a 21st century learning health system.