WCG MedAvante-ProPhase is the leading global provider of technology-enabled signal detection solutions in clinical trials of treatments for central nervous system (CNS) disorders with more than two decades of experience improving clinician-reported diagnostic and outcome measurements. MedAvante-ProPhase standardizes rating scale administration and scoring with the Virgil® Investigative Study Platform, a powerful approach to signal detection that puts the advantages of our experience in the hands of site raters as a tablet computer with unique context-sensitive electronic rating scale forms and study-specific clinical guidance, designed by clinicians for clinicians.  We prepare and qualify clinical raters with effective, measurable  rater training, and we assure ongoing data quality with Independent Review, over-read of assessment outcomes by expert central clinicians. 